5/4/2024 | 3:15 PM – 4:30 PM | Exhibit Hall F1
Poster Session—Novel Targets, Therapies, and Models of Autoimmune Diseases (PM)
Sirt2 inhibitors protect chronic inflammatory disease by improving gut epithelial barrier integrity
(P838)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 838
Abstract ID: 4282
Presenting Author:
Dan Hou, Cornell Univ.
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Complement receptor 2 as a novel therapeutic target to suppress germinal center-derived autoantibody production in a SLE mouse model
(P840)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 840
Abstract ID: 4789
Presenting Author:
Ajitanuj Rattan, Boston Children's Hosp., Harvard Med. Sch.
Co-Authors:
Danni Y. Zhu, Boston Children's Hosp.; V. Michael Holers, Univ. of Colorado Anschutz Med. Campus; Brigitte T. Huber, Tufts Univ. Sch. of Med.; Michael C. Carroll, Boston Children's Hosp., Harvard Med. Sch.;
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B cell Maturation Antigen Impacts Microglia and Macrophage Phenotypes in Neuro-autoimmune disease.
(P842)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 842
Abstract ID: 5218
Presenting Author:
Gaurav Kumar, Oklahoma Med. Res. Fndn.
Co-Authors:
Kaylea Massey, Oklahoma Med. Res. Fndn.; Rose M. Ko, Oklahoma Med. Res. Fndn.; Robert C. Axtell, Oklahoma Med. Res. Fndn.;
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Electrical stimulation of the arterial splenic nerve has durable therapeutic efficacy on murine collagen-induced arthritis.
(P844)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 844
Abstract ID: 5411
Presenting Author:
Alexandre BONDUE, CNRS
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Selective depletion of anti-dsDNA long-lived plasma cells in SLE
(P846)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 846
Abstract ID: 4635
Presenting Author:
Aditi Deokar, Dartmouth Col.
Co-Author:
Yina Huang, Geisel Sch. of Med. at Dartmouth;
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In vitro and in vivo proof-of-concept studies of extracellular protein degradation using novel M6PR-targeting chimeras (MTACs).
(P848)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 848
Abstract ID: 6012
Presenting Author:
Lisa Molz, Avilar Therapeut.
Co-Authors:
Hu Liu, Avilar Therapeut.; Nanqun Zhu, Avilar Therapeut.; Srinivasa Karra, Avilar Therapeut.; Effie Tozzo, Avilar Therapeut.;
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DB-2304, a Duality Immune Modulating Antibody‒Drug Conjugate (DIMAC) targeting BDCA2, displays strong potency in the suppression of pDC functions.
(P852)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 852
Abstract ID: 4306
Presenting Author:
Xi Li
Co-Authors:
Bing Li; Jun Yao; Shenxue Liu; Rong Shi; Yu Zhang; Zhongyuan Zhu; Yang Qiu; Haiqing Hua;
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Efficacy of a novel oral, potent, and highly selective PKCt inhibitor in the SCID T-cell transfer colitis model
(P854)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 854
Abstract ID: 4576
Presenting Author:
Jamie L Harden, Evommune
Co-Authors:
Robert L Whitener, Evommune; Andrea Kim, Evommune; Hans Hofland, Evommune; Jeegar Patel, Evommune;
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Factor VIII light chain domains of recombinant Factor VIII Fc fusion protein impact Fc effector function and CD16+ NK cell activation
(P858)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 858
Abstract ID: 4402
Presenting Author:
Basil Golding, FDA, Center for Biologics Eval. and Research (CBER)
Co-Authors:
Daniel Lagasse, FDA, Ctr. for Biologics Eval. and Res.; Zuben Sauna, FDA;
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Protective effects of Delta-8-THC against EAE-induced enteric neuropathy and neuroinflammation through regulation of miRNA-mediated signaling networks
(P860)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 860
Abstract ID: 4817
Presenting Author:
khadija kakar, Univ. of South Carolina Sch. of Med., Columbia, Balochistan University of Information Technology, Engineering, and Management Sciences (BUITEMS)
Co-Authors:
urmi Halder, Univ. of South Carolina Sch. of Med., Columbia; Mitzi nagarkatti, Univ. of South Carolina Sch. of Med., Columbia; Prakash nagarkatti, Univ. of South Carolina Sch. of Med., Columbia;
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Comprehensive evaluation of gout models for assessing drug efficacy: Insights from multifaceted approaches
(P862)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 862
Abstract ID: 4818
Presenting Author:
Jian Xiang, WuXi AppTec Co.
Co-Authors:
Yufang Wang, WuXi AppTec Co.; Ya Zhang, WuXi AppTec Co.; Zhengrong Yu, WuXi AppTec Co.; Yige Bai, WuXi AppTec Co.; Chang Shen, WuXi AppTec Co.; Tingzhu Ye, WuXi AppTec Co.; Yingying Cai, WuXi AppTec Co.; Qiyao Zhang, WuXi AppTec Co.; Qingyang Gu, WuXi AppTec Co.;
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Preclinical evaluation of Janus Kinase inhibitors in atopic dermatitis: Insights from an oxazolone-induced mouse model
(P864)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 864
Abstract ID: 4840
Presenting Author:
Xiaotuan Zhang, WuXi AppTec Company, Ltd.
Co-Authors:
Jingjing Wang, WuXi AppTec Company, Ltd.; Ya Zhang, WuXi AppTec Company, Ltd.; Dan Lu, WuXi AppTec Company, Ltd.; Qingyang Gu, WuXi AppTec Company, Ltd.; Qiyao Zhang, WuXi AppTec Company, Ltd.;
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Inhibition of p38α MAPK-MK2 axis alleviate inflammatory response in various inflammation-related disease models
(P866)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 866
Abstract ID: 4866
Presenting Author:
Tian Han, Changchun Genescience Pharmaceuticals Co., Ltd.
Co-Authors:
Tian Han, Changchun Genescience Pharmaceuticals Company, Ltd.; Donglin Fu, Changchun Genescience Pharmaceuticals Company, Ltd.; Zhilong Hu, Changchun Genescience Pharmaceuticals Company, Ltd.; Yuanfeng Xia, Changchun Genescience Pharmaceuticals Company, Ltd.; Fanglong Yang, Changchun Genescience Pharmaceuticals Company, Ltd.;
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B Cell Maturation Antigen Inhibits an Inflammatory Role of Testosterone in Experimental Autoimmune Encephalomyelitis in C57BL/6 mice.
(P868)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 868
Abstract ID: 5233
Presenting Author:
Gaurav Kumar, Oklahoma Med. Res. Fndn.
Co-Authors:
Rose M. Ko, Oklahoma Med. Res. Fndn.; Neal Bhatt, Oklahoma Med. Res. Fndn.; Robert C. Axtell, Oklahoma Med. Res. Fndn.;
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Ameliorated lupus nephritis in MRL/lpr mice with nanoparticle-mediated shRNA therapy
(P870)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 870
Abstract ID: 5361
Presenting Author:
Wenhai Shao, Univ. of Cincinnati Col. of Med.
Co-Authors:
Yuxuan Zhen, Univ. of Cincinnati Col. of Med.; David Adams; Xiaoyang Qi; Laura Conforti; Nives Zimmermann;
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Efficacy of lymphatic pump treatment in conjunction with methotrexate on rats with adjuvant-induced arthritis.
(P872)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 872
Abstract ID: 5970
Presenting Author:
Michael V Volin, Midwestern Univ., Downers Grove
Co-Authors:
Saahil Patel, Midwestern Univ., Downers Grove; Brian Zanotti, Midwestern Univ., Downers Grove; Rosalinda Monroy Del Toro, Midwestern Univ., Downers Grove; Ryan Incrocci, Midwestern Univ., Downers Grove; Michelle Swanson-Mungerson, Midwestern Univ., Downers Grove;
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IgE Neutralization Reverses Trimellitic Anhydride-Induced Urticaria in Humanized CD34+ Mice
(P874)Presentation Time: 03:15 PM–04:30 PM
Posterboard Number: 874
Abstract ID: 4825
Presenting Author:
Hao Yi
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