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5/6/2024 | 11:30 AM – 12:45 PM | Exhibit Hall F1
Late Breaking - Tumor Immunology (AM)
The combined use of statin and rapamycin treatments synergistically inhibit the proliferation of B cell Lymphoma.
(P955)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 955
Abstract ID: 5414
Presenting Author:
Zhenhan Zhu, Indiana Univ. Sch. of Med.
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We aimed to determine how many cancer-specific antgiens (neoantigens) need to be targeted by how many different TCRs for eradication of naturally heterogeneous solid tumors.
(P957)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 957
Abstract ID: 6238
Presenting Author:
Steven Wolf, Univ. of Chicago
Co-Authors:
Vasiliki Anastasopoulou, Charité – Berlin Univ. Med.; Kimberley Drousch, Charité – Berlin Univ. Med.; Markus Diehl, Univ. of Chicago; Boris Engels, Univ. of Chicago; Poh Yin Yew, Univ. of Chicago; Kazuma Kiyotani, Japanese Fndn. for Cancer Res.; Yusuke Nakamura, Japanese Fndn. for Cancer Res.; Karin Schreiber, Univ. of Chicago; Hans Schreiber, Univ. of Chicago; Matthias Leisegang, Charité – Berlin Univ. Med.;
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Antibody-TLR3 agonist-conjugates for immunotherapy of tumors
(P959)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 959
Abstract ID: 6278
Presenting Author:
Achim Temme, TU Dresden Fac. of Med. Carl Gustav Carus
Co-Authors:
Alexander Hagstotz, TU Dresden Fac. of Med. Carl Gustav Carus; Isabell Schau, TU Dresden Fac. of Med. Carl Gustav Carus; Michael Seifert, TU Dresden Fac. of Med. Carl Gustav Carus; Duran Sürün, TU Dresden Fac. of Med. Carl Gustav Carus; Stefan Zimmermann, Univ. of Fribourg; Frank Buchholz, TU Dresden Fac. of Med. Carl Gustav Carus; Luise Rupp, TU Dresden Fac. of Med. Carl Gustav Carus; Rebekka Wehner, TU Dresden Fac. of Med. Carl Gustav Carus; Marc Schmitz, TU Dresden Fac. of Med. Carl Gustav Carus; Gabriele Schackert, TU Dresden Fac. of Med. Carl Gustav Carus; Ilker Y. Eyüpoglu, TU Dresden Fac. of Med. Carl Gustav Carus;
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SIGLEC-3 (CD33) serves as an effective target in tumor progression
(P961)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 961
Abstract ID: 6292
Presenting Author:
Yi-Jyun Lin, Academia Sinica
Co-Authors:
Pei-Shan Sung, Academia Sinica; Shie-Liang Hsieh, Academia Sinica;
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Entolimod, a clinical stage flagellin derivative, improves clinically relevant chemo-immunotherapy responses in pre-clinical triple negative breast cancer
(P963)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 963
Abstract ID: 6479
Presenting Author:
Craig M. Brackett, Roswell Park Comp. Cancer Ctr.
Co-Authors:
Alyssa Aldrich, Roswell Park Comp. Cancer Ctr.; Patrick Punch, Roswell Park Comp. Cancer Ctr.; Kellee Greene, Roswell Park Comp. Cancer Ctr.; Ivan Molodtsov; Andrei Gudkov, Roswell Park Comp. Cancer Ctr.; Scott Abrams, Roswell Park Comp. Cancer Ctr.;
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The tumor immune environment in advanced breast cancer following treatment with pembrolizumab and nab-paclitaxel
(P965)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 965
Abstract ID: 7079
Presenting Author:
Apoorvi Tyagi
Co-Authors:
Iryna Voloshyna; Natalie Klar; Farbod Darvishian; Yuan Hao; Anastasia Zhurova; Loomis Cynthia; Douglas K. Marks; Sylvia Adams; Michelle Krogsgaard;
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Human implantable tertiary lymphoid organs (TLO) for solid tumor therapy: from organ chips to the clinic?
(P967)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 967
Abstract ID: 7312
Presenting Author:
Girija Goyal, Wyss Inst. for Bio. Inspired Engr. at Harvard Univ.
Co-Authors:
Lucas Barck, Wyss Inst. for Bio. Inspired Engr. at Harvard Univ.; Yunhao Zhai, Wyss Inst. for Bio. Inspired Engr. at Harvard Univ.; Pranav Prabhala, Wyss Inst. for Bio. Inspired Engr. at Harvard Univ.; Sudip Paudel, Wyss Inst. for Bio. Inspired Engr. at Harvard Univ.; Min Wen Ku, Wyss Inst. for Bio. Inspired Engr. at Harvard Univ.; Aditya P Patil, Wyss Inst. for Bio. Inspired Engr. at Harvard Univ.; Abdul R Isaacs, Wyss Inst. for Bio. Inspired Engr. at Harvard Univ.; Donald E Ingber, Wyss Inst. for Bio. Inspired Engr. at Harvard Univ.;
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Dual role of the ELK3-CYFIP2 axis regulates actin dynamics and immune responses of triple-negative breast cancer during oncogenesis
(P969)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 969
Abstract ID: 7489
Presenting Author:
Seung Hee Choi, CHA Univ.
Co-Authors:
Seung Hee Choi, CHA Univ.; Ki Seo Ryu, CHA Univ.; Kyung-Soon Park, CHA Univ.; Hye Jung Jang, CHA Univ.;
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VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms
(P971)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 971
Abstract ID: 7631
Presenting Author:
Li Wang, Cleveland Clin. Fndn.
Co-Authors:
Keman Zhang; Amin Zekari, Cleveland Clin. Fndn.; Tyler Alban, Cleveland Clin. Fndn.; Juan Dong, Cleveland Clin. Fndn.; Hieu M Ta, Cleveland Clin. Fndn.; Ajay H Zalavadia, Cleveland Clin. Fndn.; Andrelie Branicky, Cleveland Clin. Fndn.; Haoxin zhao, Case Western Reserve Univ. Sch. of Med.; Ivan Juric, Cleveland Clin. Fndn.; Hanna Husich, Cleveland Clin. Fndn.; Prerana B Parthasarathy, Cleveland Clin. Fndn.; Amit Rupani, Cleveland Clin. Fndn.; Judy A Drazba, Cleveland Clin. Fndn.; Abhishek A Chakraborty, Cleveland Clin. Fndn.; Stanley C Huang, Case Western Reserve Univ. Sch. of Med.; Timothy Chan, Cleveland Clin. Fndn.; Stefanie Avril, Case Western Reserve Univ. Sch. of Med.;
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Inhibition of lipid raft-mediated endocytosis prevents the induction of MDSCs by glioblastoma extracellular vesicles.
(P973)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 973
Abstract ID: 7665
Presenting Author:
Julio Inocencio, Albert Einstein Col. of Med.
Co-Authors:
Mohammad Asad, Albert Einstein Col. of Med.; Janatuul Fedrous, Albert Einstein Col. of Med.; Benjamin T Himes, Albert Einstein Col. of Med.;
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Adeno-Associated Virus-Mediated IL-2 Delivery in Liver Cancer: Immune Activation and Therapeutic Challenges
(P975)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 975
Abstract ID: 7686
Presenting Author:
Ya-Hui Chuang
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Aberrant glycosylation in hypoxic conditions: regulation and immune interactions
(P977)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 977
Abstract ID: 7861
Presenting Author:
Sepideh Dolatshahi, Univ. of Virginia Sch. of Med.
Co-Authors:
Shay Ladd, Univ. of Virginia; Samuel Kaufman, Univ. of Virginia;
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NK cell expansion requires the RNA-binding protein HuR to control solid tumors but not tumor metastases
(P979)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 979
Abstract ID: 7888
Presenting Author:
Sytse J Piersma, Washington Univ. Sch. of Med., St. Louis, Siteman Cancer Ctr., Barnes-Jewish Hosp. and Washington Univ. Sch. of Med., St. Louis
Co-Authors:
Sushant Bangru, Univ. of Illinois, Urbana-Champaign; Jeesang Yoon, Washington Univ. Sch. of Med., St. Louis; Tom W Liu, Washington Univ. Sch. of Med., St. Louis; Liping Yang, Washington Univ. Sch. of Med., St. Louis; Beatrice Plougastel-Douglas, Washington Univ. Sch. of Med., St. Louis; Auinash Kalsotra, Univ. of Illinois, Urbana-Champaign; Wayne M Yokoyama, Washington Univ. Sch. of Med., St. Louis;
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Interactions between Ɣẟ T-Cell subclass and patient derived pancreas cancer tumor organoid models indicate potential for cell-mediated intervention in PDAC
(P981)
Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 981
Abstract ID: 7964
Presenting Author:
Devin M Burpee, Univ. of Wisconsin Carbone Cancer Ctr.
Co-Authors:
Johnathan D Ebben, Univ. of Wisconsin Carbone Cancer Ctr.; Shahadat Hossan, Univ. of Wisconsin Carbone Cancer Ctr.; David P Turicek, Univ. of Wisconsin Carbone Cancer Ctr.; Zachary Mayhew, Univ. of Wisconsin Carbone Cancer Ctr.; Ethan Lin, Univ. of Wisconsin Carbone Cancer Ctr.; Austin Stram, Univ. of Wisconsin Carbone Cancer Ctr.; Christian Capitini, Univ. of Wisconsin Carbone Cancer Ctr.; Jeremy Kratz, Univ. of Wisconsin Carbone Cancer Ctr.;
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