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5/5/2024 | 11:30 AM – 12:45 PM | Exhibit Hall F1
Poster Session—Mechanisms Regulating B and T Cell Function (AM)
A20 is a negative regulator of both NF-κB and JNK signaling following T cell receptor stimulation in humans
(P691)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 691
Abstract ID: 4454
Presenting Author:
Gina Dabbah-Krancher, Uniformed Services Univ. of the Hlth. Sci.
Co-Authors:
Allison Ruchinskas, Uniformed Services Univ. of the Hlth. Sci.; Andrew Snow, Uniformed Services Univ. of the Hlth. Sci.;
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Molecular dynamic simulation (MDS) guided structural study on CD3 cytoplasmic tails to unravel conformational changes during TCR/CD3 triggering
(P693)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 693
Abstract ID: 4511
Presenting Author:
Liangyu Wang, Univ. of Missouri Sch. of Med., Univ. of Missouri, Columbia
Co-Authors:
Diana Gil Pages, Univ. of Missouri Sch. of Med.; John F. Cannon, Univ. of Missouri Sch. of Med.;
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Novel regulation of LAT-mediated T cell signaling by DNA-PKcs
(P697)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 697
Abstract ID: 4615
Presenting Author:
Randall Rainwater, Univ. of Arkansas for Med. Sci., Arkansas Children's Res. Inst.
Co-Authors:
Ana Azevedo-Pouly, Univ. of Arkansas for Med. Sci.; Zachary Waldrip, Univ. of Arkansas for Med. Sci.; Seana Corbin, Univ. of Arkansas for Med. Sci.; Lyle Burdine, Univ. of Arkansas for Med. Sci.; Marie Burdine, Univ. of Arkansas for Med. Sci.;
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You're (Cyto)Toxic: HDAC5 controls the activation of cytotoxic CD8+ intraepithelial lymphocytes
(P701)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 701
Abstract ID: 4684
Presenting Author:
Megan Borregard, Univ. of Chicago
Co-Authors:
Bana Jabri, Univ. of Chicago; Cezary Ciszewski, Univ. of Chicago;
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Deciphering the role of Klf2 in CD8 T cell differentiation and exhaustion during chronic infection
(P703)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 703
Abstract ID: 4786
Presenting Author:
Jian Shen, Northwestern Univ. Feinberg Sch. of Med.
Co-Authors:
Ryan Brown, Med. Col. of Wisconsin; Arjun Kharel, Northwestern Univ. Feinberg Sch. of Med.; Yuqi Zhang, Northwestern Univ. Feinberg Sch. of Med.; Ashley Brown, Med. Col. of Wisconsin; Siying Lin, Med. Col. of Wisconsin; Weiguo Cui, Northwestern Univ. Feinberg Sch. of Med.;
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IFN-beta inhibition of MLL1 mediates CD4 T cells impaired response and post-sepsis immunosuppression.
(P705)
Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 705
Abstract ID: 5015
Presenting Author:
Patricia Assis, Univ. of Michigan Med. Sch.
Co-Authors:
Ronald Allen, Univ. of Michigan Med. Sch.; Tarana Varshney, Univ. of Michigan Med. Sch.; Matthew Schaller, Univ. of Florida Col. of Med.; Jennifer Bermick, Univ. of Iowa Carver Col. of Med.; Steve Kunkel, Univ. of Michigan Med. Sch.;
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CD4 T cells endow memory B cells with unique functional properties and transcriptional programming through direct interactions
(P707)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 707
Abstract ID: 5304
Presenting Author:
Christopher D. Scharer, Emory Univ. Sch. of Med.
Co-Authors:
Sakeenah L Hicks, Emory Univ. Sch. of Med.; Mark Elliott Williams, Emory Univ. Sch. of Med.; Herbey O Padilla-Quirarte, Emory Univ. Sch. of Med.; Keenan J Wiggins, Emory Univ. Sch. of Med.;
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Sequential regulation of Lck K63-ubiquitination and autophosphorylation by the E3 ligase UBR2 and the phosphatase DUSP22 in TCR signaling
(P709)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 709
Abstract ID: 5352
Presenting Author:
Tse-Hua Tan, Natl. Hlth. Res. Inst.
Co-Author:
Huai-Chia Chuang, Natl. Hlth. Res. Inst.;
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B cell Tet2 promotes maturation of antibody responses through active DNA demethylation and OGT-mediated histone O-glycosylation of Aicda and Prdm1 loci
(P711)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 711
Abstract ID: 5454
Presenting Author:
Shili Li, UT Hlth. San Antonio
Co-Authors:
Yibo Peng, UT Hlth. San Antonio; Zhimin Yang, UT Hlth. San Antonio; Xin Li, UT Hlth. San Antonio; Hong Zan, UT Hlth. San Antonio; Paolo Casali, UT Hlth. San Antonio;
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Harnessing temperature-dependent STING signaling to reprogram regulatory T cells and enhance effector T cell immunity.
(P713)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 713
Abstract ID: 5584
Presenting Author:
Rachael C Smith, Vanderbilt Univ.
Co-Authors:
Darren R Heintzman, Vanderbilt Univ.; Emilie L Fisher, Vanderbilt Univ.; Kelsey C Voss, Vanderbilt Univ. Med. Ctr.; Xiang Ye, Vanderbilt Univ. Med. Ctr.; Yasmine Toudji, Vanderbilt Univ.; Channing Chi, Vanderbilt Univ. Med. Ctr.; Jacob A Schulman, Vanderbilt Univ.; Jeffrey C Rathmell, Vanderbilt Univ. Med. Ctr.; John T Wilson, Vanderbilt Univ.;
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Mechanism of Treg conversion to exTreg in Atherosclerosis
(P715)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 715
Abstract ID: 5677
Presenting Author:
Qingkang Lyu, Med. Col. of Georgia, Augusta Univ.
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CARD11-dependent signaling in T cells is critical for the activation of multiple AP-1 transcription factor complexes.
(P721)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 721
Abstract ID: 5984
Presenting Author:
Bradly M. Bauman, Uniformed Services Univ. of the Hlth. Sci., Henry M. Jackson Foundation for the Advancement of Military Medicine
Co-Authors:
Jeffrey R Stinson, Uniformed Services Univ. of the Hlth. Sci.; Andrew Frank, Henry M. Jackson Fndn. for the Advancement of Mil. Med.; Gauthaman Sukumar, Henry M. Jackson Fndn. for the Advancement of Mil. Med.; Clifton L Dalgard, Uniformed Services Univ. of the Hlth. Sci.; Andrew L Snow, Uniformed Services Univ. of the Hlth. Sci.;
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Defining the Transcriptional Regulation of NR2F6 in TH17 Cell Responses
(P723)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 723
Abstract ID: 6058
Presenting Author:
Adrianna Wilson, Scripps Res. Skaggs Grad. Sch. of Chem. and Bio. Sci., Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation & Technology
Co-Authors:
Sean Campbell; Sarah Mosure; Jonathan Chuck; Laura Solt;
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Deciphering the genetic architecture of antibody repertoire development
(P725)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 725
Abstract ID: 5924
Presenting Author:
Oscar Rodriguez, Univ. of Louisville Sch. of Med.
Co-Authors:
Xiang Qiu, NIA, NIH; Ranjan Sen, NIA, NIH; Corey Watson, Univ. of Louisville Sch. of Med.;
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Elucidating the Transcriptional Role of the Nuclear Receptor RORα in CD8+ T Cell Memory vs Effector Cell Development
(P727)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 727
Abstract ID: 4701
Presenting Author:
Jonathan Chuck, Scripps Res. Skaggs Grad. Sch. of Chem. and Bio. Sci., Wertheim Univ. of Florida Scripps Inst.
Co-Authors:
Avanti S Puvvala, Florida Atlantic Univ. Wilkes Honors Col.; Sean Campbell, Wertheim Univ. of Florida Scripps Inst.; Laura A Solt, Wertheim Univ. of Florida Scripps Inst.;
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Examining the relationship between CD36 and T-bet expression in B cells.
(P729)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 729
Abstract ID: 4467
Presenting Author:
Andrea Paredes, St. Mary's Univ.
Co-Authors:
G. Sophia Noriega, St. Mary's Univ.; Valeriia Klepikova, St. Mary's Univ.; Carlo Vanz, UT Hlth. San Antonio; Emma C Collins, UT Hlth. San Antonio; Elizabeth A Leadbetter, UT Hlth. San Antonio; Benjamin T. Enslow, St. Mary's Univ.;
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BLIMP-1 and CEACAM1 cooperate to regulate human regulatory T cell proliferation and function
(P731)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 731
Abstract ID: 5060
Presenting Author:
Ying Ding, Univ. of Miami Miller Sch. of Med.
Co-Authors:
Aixin Yu, Univ. of Miami Miller Sch. of Med.; Milos Vujanac, Univ. of Miami Miller Sch. of Med.; Sabrina N. Copsel, Univ. of Miami Miller Sch. of Med.; Alejandro Moro, Univ. of Miami Miller Sch. of Med.; Luis Nivelo, Univ. of Miami Miller Sch. of Med.; Nicolas Tchitchek, Sorbonne Univ.; Michelle Rosenzwajg, Sorbonne Univ.; Alejandro V. Villarino, Univ. of Miami Miller Sch. of Med.; Robert B. Levy, Univ. of Miami Miller Sch. of Med.; David Koatzmann, Sorbonne Univ.; Thomas R. Malek, Univ. of Miami Miller Sch. of Med.;
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Resolving haplotype variation and complex genetic architecture in the human immunoglobulin kappa and lambda chain loci in individuals of diverse ancestry
(P733)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 733
Abstract ID: 5749
Presenting Author:
Eric Engelbrecht, Univ. of Louisville Sch. of Med.
Co-Authors:
Oscar L Rodriguez, Univ. of Louisville Sch. of Med.; Kaitlyn Shields, Univ. of Louisville Sch. of Med.; Steven Schultze, Univ. of Louisville Sch. of Med.; David Tieri, Univ. of Louisville Sch. of Med.; Uddalok Jana, Univ. of Louisville Sch. of Med.; William Lees, Bar-Ilan Univ.; Melissa L Smith, Univ. of Louisville Sch. of Med.; Corey T Watson, Univ. of Louisville Sch. of Med.;
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The first case of autosomal recessive CADINS-like disease caused by novel compound heterozygous hypomorphic variants in CARD11.
(P735)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 735
Abstract ID: 5377
Presenting Author:
Alison R Spratt, Uniformed Services Univ. of the Hlth. Sci., Henry M. Jackson Fndn. for the Advancement of Mil. Med.
Co-Authors:
Boaz Palterer, Univ. degli Studi di Firenze; Bradly M Bauman, Uniformed Services Univ. of the Hlth. Sci.; Lorenzo Salvati, Univ. degli Studi di Firenze; Alessio Mazzoni, Univ. degli Studi di Firenze; Laura Maggi, Univ. degli Studi di Firenze; Manuela Capone, Univ. degli Studi di Firenze; Anna Vanni, Univ. degli Studi di Firenze; Aldesia Provenzano, Ospedale Pediatrico Meyer; Sabrina Giglio, Ospedale Pediatrico Meyer; Lorenzo Cosmi, Univ. degli Studi di Firenze; Francesco Liotta, Univ. degli Studi di Firenze; Paola Parronchi, Univ. degli Studi di Firenze; Francesco Annunziato, Univ. degli Studi di Firenze; Andrew L Snow, Uniformed Services Univ. of the Hlth. Sci.;
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Deletion of MOF in CD4 T cells results in mitochondrial dysfunction, Th17 polarization, and colonic inflammation.
(P737)Presentation Time: 11:30 AM–12:45 PM
Posterboard Number: 737
Abstract ID: 5762
Presenting Author:
Felipe Teixeira Lima, Univ. of Florida
Co-Authors:
Yana Goddard, Univ. of Florida; Matthew Wheeler, Univ. of Florida; Ganlin Qu, Univ. of Florida; Nikolas Diodati, Univ. of Florida; Luis Sordo-Vieira, Univ. of Florida; Arantxa V. Lazarte, Univ. of Florida; Matthew A. Schaller, Univ. of Florida; Borna Mehrad, Univ. of Florida;
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