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5/5/2024 | 9:45 AM – 11:15 AM | Room W185
Block Symposium—Innate Immune Responses in Health and Disease
Moderators
Fayyaz Sutterwala, Cedars-Sinai Med. Ctr., USA
Suzanne Cassel, Cedars-Sinai Med. Ctr., USA
NLRP3 Cys126 palmitoylation by ZDHHC7 Promotes Inflammasome Activation
Presentation Time: 09:45 AM–10:00 AM
Abstract ID: 4283 - B
Presenting Author:
Tao Yu, Howard Hughes Med. Inst., Cornell Univ.
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Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS
Presentation Time: 10:00 AM–10:15 AM
Abstract ID: 5912 - B
Presenting Author:
Kimberly A Wodzanowski, Univ. of Pennsylvania Perelman Sch. of Med.
Co-Authors:
Daniel C Akuma, Univ. of Pennsylvania Sch. of Vet. Med.; Ronit Schwartz Wertman, Univ. of Pennsylvania Sch. of Vet. Med.; Patrick M Exconde, Univ. of Pennsylvania Perelman Sch. of Med.; Victor R Vazquez Marrero, Univ. of Pennsylvania Perelman Sch. of Med.; Chukwuma E Odunze, Univ. of Maryland, Col. Park; Daniel Grubaugh, Univ. of Pennsylvania Sch. of Vet. Med.; Sunny Shin, Univ. of Pennsylvania Perelman Sch. of Med.; Cornelius Y Taabazuing, Univ. of Pennsylvania Perelman Sch. of Med.; Igor E Brodsky, Univ. of Pennsylvania Sch. of Vet. Med.;
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Host-pathogen interactions in Leptospirosis
Presentation Time: 10:15 AM–10:30 AM
Abstract ID: 5238 - B
Presenting Author:
Suman Gupta, Cedars-Sinai Med. Ctr.
Co-Authors:
James Matsunaga, VA Greater Los Angeles Healthcare Sys.; David Haake, VA Greater Los Angeles Healthcare Sys.; Fayyaz Sutterwala, Cedars-Sinai Med. Ctr.; Suzanne Cassel, Cedars-Sinai Med. Ctr.;
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Loss of myeloid-KLF2 mediates LPS-induced mortality in neonatal pups by NLRP3 inflammasome signaling and altered neutrophil aging
Presentation Time: 10:30 AM–10:45 AM
Abstract ID: 5500 - B
Presenting Author:
Sriram Satyavolu, Case Western Reserve Univ. Sch. of Med.
Co-Authors:
Devashis Mukherjee, Case Western Reserve Univ. Sch. of Med.; Asha Thomas, Case Western Reserve Univ. Sch. of Med.; Lalitha Nayak, Case Western Reserve Univ. Sch. of Med.;
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Airway epithelial cell-specific deletion of EGFR in Scnn1b transgenic mice modulates inflammatory responses but doesn’t affect muco-obstructive features of lung disease
Presentation Time: 10:45 AM–11:00 AM
Abstract ID: 4790 - B
Presenting Author:
Ishita Choudhary, North Carolina State Univ. Col. of Vet. Med.
Co-Authors:
Kshitiz Paudel, North Carolina State Univ. Col. of Vet. Med.; Rahul Kumar, North Carolina State Univ. Col. of Vet. Med.; Sonika Patial, North Carolina State Univ. Col. of Vet. Med.; Yogesh Saini, North Carolina State Univ. Col. of Vet. Med.;
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Air pollution PM2.5 uptake by macrophages induces NLRP3 inflammasome-dependent IL1ß release through pro-inflammatory cytokine secretion and mitochondrial Complex I superoxide anion production.
Presentation Time: 11:00 AM–11:15 AM
Abstract ID: 4400 - B
Presenting Author:
Lourdes Caceres, Univ. of Chicago, Univ. Hosp. Freiburg
Co-Authors:
Tijani Abogunloko, Univ. Hosp. Freiburg; Sara Malchow, Univ. Hosp. Freiburg; Fabienne Ehret, Univ. Hosp. Freiburg; Julian Merz, Univ. Hosp. Freiburg; Natalia Magnani, Univ. de Buenos Aires; Larissa Fischer, Univ. of Freiburg; Oliver Gorka, Univ. of Freiburg; Eva Rog-Zielinska, Univ. of Freiburg; Olaf Groß, Univ. of Freiburg; Pablo Evelson, Univ. de Buenos Aires; Dennis Wolf, Univ. Hosp. Freiburg; Timoteo Marchini, Univ. Hosp. Freiburg;
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