Tumor derived acidity enhances T_reg suppressive functions against anti-tumor T_effs

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Presentation Time: 12:45 PM–01:00 PM
Abstract ID: 5593 - B

Presenting Author:
Nikita L Mani, Northwestern Univ. Feinberg Sch. of Med.

Co-Authors:
Samuel E Weinberg, Northwestern Med.; Deyu Fang, Northwestern Univ. Feinberg Sch. of Med.;

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SLAMF7+ CD8+ T cells exhibit decreased anti-tumor responses in renal cell carcinoma

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Presentation Time: 01:00 PM–01:15 PM
Abstract ID: 5876 - B

Presenting Author:
Lena Wirth, Yale Univ.

Co-Authors:
Miya Hugaboom, Yale Sch. of Med.; Kelly Street, Keck Sch. of Med. of Univ. of Southern California; Neil Ruthen, Dana-Farber Cancer Inst.; Opeyemi Jegede, Dana-Farber Cancer Inst.; Nicholas Schindler, Yale Sch. of Med.; David McDermott, Beth Israel Deaconess Med. Ctr., Harvard Med. Sch.; Elizabeth Plimack, Fox Chase Cancer Ctr., Temple Hlth.; Jeffrey Sosman, Northwestern Univ.; Naomi Haas, Univ. of Pennsylvania; Michael Hurwitz, Yale Sch. of Med.; Hans Hammers, Univ. of Texas Southwestern Med. Ctr.; Sabina Signoretti, Brigham and Women's Hosp.; Michael Atkins, Lombardi Comp. Cancer Ctr., Georgetown Univ.; Catherine Wu, Dana-Farber Cancer Inst.; David Braun, Yale Sch. of Med.;

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β-adrenergic signaling regulates erythropoiesis and through it; cancer immunity

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Presentation Time: 01:15 PM–01:30 PM
Abstract ID: 5658 - B

Presenting Author:
Arshmeet K Chawla, UConn Hlth.

Co-Authors:
Adam T Hagymasi, UConn Hlth.; Rory J Geyer, UConn Hlth.; Ion I Mandoiu, UConn; Kenneth R Peterson, Univ. of Kansas Med. Ctr.; Vanessa M Scanlon, UConn Hlth.; Pramod K Srivastava, UConn Hlth.; James T Nevin, UConn Hlth.;

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Targeting Pim2 improves effector function and longevity of T cells in cancer immunotherapy through regulating autophagy

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Presentation Time: 01:30 PM–01:45 PM
Abstract ID: 5055 - B

Presenting Author:
Yongxia Wu, Med. Col. of Wisconsin

Co-Authors:
Linlu Tian, Med. Col. of Wisconsin; Allison Pugel, Med. Col. of Wisconsin; Xue-Zhong Yu, Med. Col. of Wisconsin;

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Vasoactive intestinal peptide suppresses T cell activation via VPAC1 receptor and limits anti-tumor immunity.

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Presentation Time: 01:45 PM–02:00 PM
Abstract ID: 5568 - B

Presenting Author:
Tenzin Passang, Winship Cancer Inst., Emory Univ.

Co-Authors:
Shuhua Wang, Winship Cancer Inst., Emory Univ.; Hanwen Zhang, Winship Cancer Inst., Emory Univ.; Jian-Ming Li, Winship Cancer Inst., Emory Univ.; Maggie Phillips, Winship Cancer Inst., Emory Univ.; Isaac Karpovsky, Winship Cancer Inst., Emory Univ.; Sruthi Ravindranathan, Winship Cancer Inst., Emory Univ.; Edmund K. Waller, Winship Cancer Inst., Emory Univ.;

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CD8 T cells with an exhaustion-like phenotype remain highly functional in hematologic tumors

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Presentation Time: 02:00 PM–02:15 PM
Abstract ID: 5980 - B

Presenting Author:
Simone A Minnie, Fred Hutchinson Cancer Res. Ctr.

Co-Authors:
Olivia G Waltner, Fred Hutchinson Cancer Res. Ctr.; Ping Zhang, Fred Hutchinson Cancer Res. Ctr.; Shuichiro Takahashi, Fred Hutchinson Cancer Res. Ctr.; Nicole S Nemychenkov, Fred Hutchinson Cancer Res. Ctr.; Kathleen S Ensbey, Fred Hutchinson Cancer Res. Ctr.; Samuel RW Legg, Fred Hutchinson Cancer Res. Ctr.; Melissa Comstock, Fred Hutchinson Cancer Res. Ctr.; Julie R Boiko, Fred Hutchinson Cancer Res. Ctr.; Shruti S Bhise, Fred Hutchinson Cancer Res. Ctr.; Alec B Wilkens, Fred Hutchinson Cancer Res. Ctr.; Motoko Koyama, Fred Hutchinson Cancer Res. Ctr.; Madhav V Dhodapkar, Emory Univ.; Marta Chesi, Mayo Clin., Arizona; Stanley R Riddell, Fred Hutchinson Cancer Res. Ctr.; Damian J Green, Fred Hutchinson Cancer Res. Ctr.; Andrew Spencer; Scott N Furlan, Fred Hutchinson Cancer Res. Ctr.; Geoffrey R Hill, Fred Hutchinson Cancer Res. Ctr.;

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