Mitochondrial transcription is essential for the potent antitumor stem memory T cells

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Presentation Time: 09:45 AM–10:00 AM
Abstract ID: 4268 - B

Presenting Author:
Soundharya Kumaresan, Winship Cancer Inst., Emory Univ.

Co-Authors:
Guillermo Omar Rangel Rivera, Winship Cancer Inst., Emory Univ.; Hannah M Knochelmann, Winship Cancer Inst., Emory Univ.; Aubrey S Smith, Winship Cancer Inst., Emory Univ.; Ayana T Ruffin, Winship Cancer Inst., Emory Univ.; Anna C Cole, Winship Cancer Inst., Emory Univ.; Megen C Wittling, Winship Cancer Inst., Emory Univ.; Megan M Wyatt, Winship Cancer Inst., Emory Univ.; Michael C Lowe, Emory Univ.; Gregory B Lesinski, Winship Cancer Inst., Emory Univ.; Chrystal M Paulos, Winship Cancer Inst., Emory Univ.;

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CD27 signaling inhibits tumor metastasis via CD8+ T cell-independent mechanisms

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Presentation Time: 10:00 AM–10:15 AM
Abstract ID: 5142 - B

Presenting Author:
Eswara Rao Puppala, Univ. of Maryland Greenebaum Comp. Cancer Ctr.

Co-Authors:
Long Wu, Univ. of Maryland Greenebaum Comp. Cancer Ctr.; Xiaoxuan Fan, Univ. of Maryland, Baltimore; Xuefang Cao, Univ. of Maryland Greenebaum Comp. Cancer Ctr.;

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Fate mapping LAG3⁺ exhausted CD8⁺ T cells.  

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Presentation Time: 10:15 AM–10:30 AM
Abstract ID: 5289 - B

Presenting Author:
Vaishali Aggarwal, Univ. of Pittsburgh Sch. of Med., UPMC Hillman Cancer Ctr.

Co-Authors:
Chang Liu, Univ. of Pittsburgh Sch. of Med.; Cui Jian, Univ. of Pittsburgh Sch. of Med.; Haiguang Wang, Univ. of Pittsburgh Sch. of Med.; Sasikanth Manne, Univ. of Pennsylvania Perelman Sch. of Med.; Kate M. M. Vignali, Univ. of Pittsburgh Sch. of Med.; Edward John Wherry, Univ. of Pennsylvania Perelman Sch. of Med.; Creg J. Workman, Univ. of Pittsburgh Sch. of Med.; Dario A. A. Vignali, Univ. of Pittsburgh Sch. of Med.;

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Chromatin remodeler ACTL6A in CD8⁺ T cells promotes antitumor immunity

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Presentation Time: 10:30 AM–10:45 AM
Abstract ID: 4241 - B

Presenting Author:
Bogang Wu, Massachusetts Gen. Hosp., Harvard Med. Sch.

Co-Authors:
Win Thant, Massachusetts Gen. Hosp., Harvard Med. Sch.; Elena Bitman, Massachusetts Gen. Hosp., Harvard Med. Sch.; Ting Liu, Massachusetts Gen. Hosp., Harvard Med. Sch.; Leif W. Ellisen, Massachusetts Gen. Hosp., Harvard Med. Sch.;

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PD-L1 deletion on T cells results in a pro-tumorigenic environment

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Presentation Time: 10:45 AM–11:00 AM
Abstract ID: 5464 - B

Presenting Author:
Konstantinos Aliazis, Beth Israel Deaconess Med. Ctr., Harvard Med. Sch.

Co-Authors:
Rushil Shah, Beth Israel Deaconess Med. Ctr., Harvard Med. Sch.; Sasitorn Yenyuwadee, Beth Israel Deaconess Med. Ctr., Harvard Med. Sch.; Rinku Pal, Beth Israel Deaconess Med. Ctr., Harvard Med. Sch.; Vassiliki A Boussiotis, Beth Israel Deaconess Med. Ctr., Harvard Med. Sch.;

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Understanding the role of TNFR2 signaling in CD8 T cell exhaustion.

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Presentation Time: 11:00 AM–11:15 AM
Abstract ID: 5509 - B

Presenting Author:
Alexandra M Hoyt-Miggelbrink, Duke Univ.

Co-Authors:
Jessica Waibl Polania, Duke Univ.; Luke Wachsmuth, Duke Univ.; Selena Lorrey, Duke Univ.; Daniel Wilkinson, Duke Univ.; Kelly Hotchkiss, Duke Univ.; Emily Lerner, Duke Univ.; Sarah Cook Quackenbush, Duke Univ.; Saskia Hemmers, Duke Univ.; Kathy Ayasoufi, Duke Univ.; Peter Fecci, Duke Univ.;

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