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5/6/2024 | 12:45 PM – 2:15 PM | Room W175
Block Symposium—Novel Strategies in CAR T Therapies
Moderators
Alison Kohan, Univ. of Pittsburgh
Gang Xin, Ohio State Univ. Col. of Med.
Postprandial changes to systemic metabolism imprint durable changes on T cell immune responses
Presentation Time: 12:45 PM–01:00 PM
Abstract ID: 4724 - B
Presenting Author:
Alok Kumar, Univ. of Pittsburgh
Co-Authors:
Dayana Rivadienera, Univ. of Pittsburgh; Greg M Delgoffe, Univ. of Pittsburgh; Amanda Poholek, Univ. of Pittsburgh; Alison Kohan, Univ. of Pittsburgh;
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CD3ζ ITAM diversity determines chimeric antigen receptor force and function.
Presentation Time: 01:00 PM–01:15 PM
Abstract ID: 5325 - B
Presenting Author:
Hilda Echelibe, Univ. of Utah
Co-Authors:
Shubhabrata Majumdar, Baylor Col. of Med.; Elizabeth Kolawole, Univ. of Utah; Baoyu Liu, Univ. of Utah; Maria Bettini, Univ. of Utah; Brian Evavold, Univ. of Utah; Matthew Bettini, Univ. of Utah;
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Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion
Presentation Time: 01:15 PM–01:30 PM
Abstract ID: 5734 - B
Presenting Author:
Nikolaos Sgourakis, Univ. of Pennsylvania
Co-Authors:
Yi Sun, Univ. of Pennsylvania; Tyler Florio, Univ. of Pennsylvania; Sagar Gupta, Univ. of Pennsylvania; Quinlen Marshall, Univ. of Pennsylvania; Samuel Garfinkle, Univ. of Pennsylvania; Michael Young, Univ. of Pennsylvania; Georgia Papadaki, Univ. of Pennsylvania; Hau Truong, Penn Med.; Peiyao Li, Univ. of Pennsylvania; Emily Mycek, Univ. of Pennsylvania; Alvin Farrel, Univ. of Pennsylvania; Mark Yarmarkovich, NYU Langone Hlth.; Leena Mallik, Penn Med.; John Maris, Univ. of Pennsylvania;
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Novel tumor-specific Vδ1/3 γδ CAR T cells effectively control solid tumors
Presentation Time: 01:30 PM–01:45 PM
Abstract ID: 4696 - B
Presenting Author:
Luis U Lopez Bailon, Duke Cancer Inst., Duke Univ. Sch. of Med.
Co-Authors:
Carmen M Anadon, Duke Cancer Inst.; Ricardo A Chaurio, Duke Cancer Inst.; Jessica A Mine, Duke Univ. Sch. of Med.; Noah Plappert, Duke Univ. Sch. of Med.; Scott Antonia, Duke Cancer Inst.; Jose R Conejo-Garcia, Duke Univ. Sch. of Med.;
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Activation of APOBEC3B and Induced APOBEC3 Mutations in Self-Inactivating Lentiviral-Based CAR T Cell Production Decreases the Efficiency of CAR T Cell Production
Presentation Time: 01:45 PM–02:00 PM
Abstract ID: 4781 - B
Presenting Author:
Jack Swanson, Mayo Clin. Grad. Sch. of Biomed. Sci., Mayo Clin., Minnesota
Co-Authors:
Jason Tonne, Mayo Clin., Minnesota; Richard Vile, Mayo Clin., Minnesota;
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