5/5/2024 | 4:30 PM – 6:00 PM | Room W178
Block Symposium—Therapeutic Intervention for Treating Immune Dysregulation in Inflammation and Cancer
Moderators
Ivan Mascanfroni, Seismic Therapeut.
Xiaoguang Li, AbbVie
Tumor expressed BCAM impedes anti-tumor T cell immunity and can be targeted therapeutically
Presentation Time: 04:30 PM–04:45 PM
Abstract ID: 5466 - B
Presenting Author:
Dallas B Flies, NextCure
Co-Authors:
Linjie Tian, NextCure; Rachel O'Neill, NextCure; Daniel P Fitzgerald, NextCure; Sasan Sharee, NextCure; Jahangheer Shaik, NextCure; Jason Bosiacki, NextCure; Ana Paucarmayta, NextCure; Kushal Prajapati, NextCure; Solomon Langermann, NextCure; Paulus Mrass, Univ. of New Mexico Comp. Cancer Ctr.;
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Mapping associated cell subsets (M.A.C.S): a molecular assessment of macrophage heterogeneity across tissue and disease linking in vitro to in vivo
Presentation Time: 04:45 PM–05:00 PM
Abstract ID: 5035 - B
Presenting Author:
Kathryn Bound, Pfizer
Co-Authors:
Roxanne Martino, Pfizer; Stephen M Christensen, Pfizer; Marc H Wadsworth II, Pfizer; Saurav De, Pfizer; Iana Garcia, Pfizer; David Logan, Pfizer; Matthew P Lech, Pfizer; Kellie M Kravarik, Pfizer; Ken Dower, Pfizer; Thomas A Wynn, Pfizer; Alexander M.S. Barron, Pfizer; Kevin M Hart, Pfizer; Thomas Fabre, Pfizer;
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ANB032, a novel BTLA agonist monoclonal antibody, reduced T cell proliferation, inflammatory cytokine secretion and prevented graft versus host disease in a mouse model
Presentation Time: 05:00 PM–05:15 PM
Abstract ID: 5691 - B
Presenting Author:
Martin E Dahl
Co-Authors:
Matthew Hsu; Cheryl Schendel; Chris Haines; Pejman Soroosh; Stephen Parmley; Eric Hare, AnaptysBio, Inc;
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Impact of Urolithin A supplementation, a mitophagy activator on mitochondrial health of immune cells (MitoIMMUNE) - A randomized, double-blind, placebo-controlled trial in healthy adults
Presentation Time: 05:15 PM–05:30 PM
Abstract ID: 4882 - B
Presenting Author:
Dominic Denk
Co-Authors:
Anurag Singh; Herbert G. Kasler; Johanna Gorol; Eric Verdin; Florian R Greten;
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A novel PTPN2 protein isoform differentially regulates Inflammation
Presentation Time: 05:30 PM–05:45 PM
Abstract ID: 4253 - B
Presenting Author:
Xiaoguang Li, AbbVie
Co-Authors:
Fedik Rahimov, AbbVie; Arthur Ma, AbbVie; Tiankai Han, AbbVie; Timothy Radstake, AbbVie; Amlan Biswas, AbbVie; Kanstantsin Katlinski, AbbVie;
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Selective small-molecule PKC-theta inhibitors effectively block TCR-mediated activation of naïve peripheral blood and tissue resident memory T cells
Presentation Time: 05:45 PM–06:00 PM
Abstract ID: 5925 - B
Presenting Author:
Robert L. Whitener
Co-Authors:
Jamie L. Harden; Hans Hofland; Jeegar Patel;
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